Gene expression patterns define pathways correlated with loss of differentiation in lung adenocarcinomas
โ Scribed by Chad Creighton; Samir Hanash; David Beer
- Book ID
- 117105259
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 111 KB
- Volume
- 540
- Category
- Article
- ISSN
- 0014-5793
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Codon 12 of the K-ras oncogene was screened for mutations in 65 surgically-resected primary pulmonary adenocarcinomas and in tissue foci of alveolar atypical hyperplasia (AAH) by a polymerase chain reaction (PCR)-based method. Mutations in either position or position 2 of codon 12 were detected in 1
## Abstract ## BACKGROUND Regenerating gene I (REG) was identified as a growth factor for pancreatic islet beta cells. Enhanced REG expression was observed during the healing of gastric mucosa. REG expression was observed in various tumors including gastric carcinoma, but to the authors' knowledge