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Gene Encoding the α Chain of the T-Cell Receptor is Moved Immediately Downstream of c-myc in a Chromosomal 8;14 Translocation in a Cell Line from a Human T-Cell Leukemia

✍ Scribed by Elizabeth A. Shima, Michelle M. Le Beau, Timothy W. McKeithan, Jun Minowada, Louise C. Showe, Tak W. Mak, Mark D. Minden, Janet D. Rowley and Manuel O. Diaz


Book ID
123632856
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
1007 KB
Volume
83
Category
Article
ISSN
0027-8424

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An (8;14)(q24;q11) translocation involvi
✍ James K. Park; Timothy W. McKeithan; Michelle M. le Beau; Mitchell A. Bitter; Wi 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 796 KB

We describe a t(8; I4)(q24;q I I) involving the T-cell receptor a-chain gene (TCRA) and the 3' region of the MYC protooncogene in a B-cell lymphoma. The 6-cell origin of this tumor was determined by its histological architecture, by immunophenotypic analysis, and by Southern analysis of immunoglobul