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Gene Defects in β-Thalassemia and Their Prenatal Diagnosis

✍ Scribed by HAIG H. KAZAZIAN JR.; CAROL E. DOWLING; CORINNE D. BOEHM; TINA C. WARREN; EFFROSINI P. ECONOMOU; JOEL KATZ; STYLIANOS E. ANTONARAKIS


Book ID
119864520
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
964 KB
Volume
612
Category
Article
ISSN
0890-6564

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β-Thalassemia mutations in Singapore — a
✍ Ivy S. L. Ng; Joyce B. K. Ong; Cheng Lim Tan; Hai Yang Law 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 359 KB

The strategy for early prenatal diagnosis of [3thalassemia in Singapore by direct detection of the mutant 13-globin gene requires the spectrum of mutations producing the disorder in this population to be characterized. We analyzed 134 13-thalassemia alleles from Singapore by specific oligonucleotide