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Gene clusters and polycistronic transcription in eukaryotes

✍ Scribed by Thomas Blumenthal

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 92 KB
Volume: 20
Category: Article
ISSN: 0265-9247
DOI: 10.1002/(sici)1521-1878(199806)20:6<480::aid-bies6>3.0.co;2-q

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✦ Synopsis

Sometimes genes are arranged nonrandomly on the chromosomes of eukaryotes. This review considers instances of gene clusters in which two genes or more are expressed from a single promoter. This includes cases in which a polycistronic pre-mRNA is processed to make monocistronic mRNAs in nematodes, as well as isolated examples of polycistronic mRNAs found in mammals, flies, and perhaps plants.

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