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Gene cloning, expression and purification of human mitochondrial tRNALeu(UUR)and its mutant

✍ Scribed by Weiguo Han; Li Chen; Jing Liu; Xiliang Zha; Youxin Jin; Debao Wang

Publisher
Science in China Press (SCP)
Year
2001
Tongue
English
Weight
556 KB
Volume
44
Category
Article
ISSN
1674-7305

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✍ Tsukuda, K.; Suzuki, Y.; Kameoka, K.; Osawa, N.; Goto, Y.; Katagiri, H.; Asano, πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 114 KB πŸ‘ 2 views

To investigate the prevalence and clinical characteristics of diabetes mellitus caused by mitochondrial gene mutations in the tRNA Leu(UUR) region, a known 'hot spot' for pathogenic mutations, we screened 440 diabetic patients with diabetic mothers for 11 mitochondrial gene mutations reported in mit