Functional expression of p-glycoprotein
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X. Declèves; A. Regina; J.-L. Laplanche; F. Roux; B. Boval; J.-M. Launay; J.-M.
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Article
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2000
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John Wiley and Sons
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English
β 164 KB
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Although it has been well established that the drug efflux pump P-glycoprotein (P-gp) protects the brain against the entry of cytotoxic drugs, its real in situ localization, i.e., at brain capillary endothelial cells or on astrocyte foot processes, is still controversial. The aim of this study was t