In the present study, we examined whether the level of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) in leukocyte DNA is higher in lung cancer patients compared to controls. Factors that may influence oxidative stress, such as antioxidant vitamins, were also determined. These parameters were analy
Gender difference in DNA adduct levels among nonsmoking lung cancer patients
β Scribed by Ya-Wen Cheng; Ling-Ling Hsieh; Pin-Pin Lin; Chao-Pin Chen; Chih-Yi Chen; Ton-Sen Lin; Jan-Ming Su; Huei Lee
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 132 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.1037
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## Abstract It is controversial whether women have a higher lung cancer susceptibility compared to men. We previously reported higher levels of smokingβrelated bulky DNA adducts in female lungs. In a pilot study (27 cases), we also found a higher level of female lung cytochrome P4501A1 (CYP1A1) gen