Geminal-Dialkyl-Effect-Controlled Site Selectivity of Fe(I)-Mediated C  H/C  C Bond Activation of Aliphatic Ketones

✍ Scribed by Schröder, Detlef ;Bowie, John H. ;Stringer, M. B. ;Schwarz, Helmut

• Publisher: Wiley (John Wiley & Sons)
• Year: 1991
• Tongue: English
• Weight: 179 KB
• Volume: 124
• Category: Article
• ISSN: 0009-2940
• DOI: 10.1002/cber.19911240733

✦ Synopsis

Bond activation, C -H, C -C / Transition-metal ions / Tandem mass spectrometry / Geminal dialkyl effect Depending on the internal energy content, due to the operation of a geminal dialkyl effect, the Fe+-mediated dehydro-genation of a,a-dimethyl-substituted ketones preferably involves the more substituted alkyl chain.