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Gemcitabine synergistically enhances the effect of adenovirus gene therapy through activation of the CMV promoter in pancreatic cancer cells

✍ Scribed by Onimaru, M; Ohuchida, K; Egami, T; Mizumoto, K; Nagai, E; Cui, L; Toma, H; Matsumoto, K; Hashizume, M; Tanaka, M


Book ID
109842778
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
671 KB
Volume
17
Category
Article
ISSN
0929-1903

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## Abstract ## Background Hybrid adeno‐retroviral vector systems utilize the high efficiency of adenovirus transduction to direct the __in situ__ production of retroviral progeny. In this study, we show that a single‐step transduction of glioma cells with trans‐complementing hybrid adeno‐retrovira