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Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells

✍ Scribed by Bocci, G; Fioravanti, A; Orlandi, P; Bernardini, N; Collecchi, P; Del Tacca, M; Danesi, R


Book ID
109998586
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
338 KB
Volume
93
Category
Article
ISSN
0007-0920

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## Abstract Vascular endothelial growth factor (VEGF) is the major pro‐angiogenic factor for most tumors. VEGF expression has been shown to be associated with a poor prognosis in human pancreatic cancer. The purpose of our study was to determine the effect of blockade of VEGF receptor‐2 activity wi