GDNF and BMP7 in early kidney development
โ Scribed by Frank Conlon
- Book ID
- 114174390
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 55 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0168-9525
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Bone morphogenetic proteins (BMPs) are typically members of the transforming growth factor โค (TGF-โค) family with diverse roles in embryonic development. At least five genes with homology to BMPs are expressed during Xenopus development, along with their receptors and intracellular signalling pathway
Signaling by GDNF through the Ret receptor is required for normal growth of the ureteric bud during kidney development. However, the precise role of GDNF/Ret signaling in renal branching morphogenesis and the specific responses of ureteric bud cells to GDNF remain unclear. Recent studies have provid