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Gastrointestinal Toxicity, Antiinflammatory Activity, and Superoxide Dismutase Activity of Copper and Zinc Complexes of the Antiinflammatory Drug Indomethacin

✍ Scribed by Dillon, Carolyn T.; Hambley, Trevor W.; Kennedy, Brendan J.; Lay, Peter A.; Zhou, Qingdi; Davies, Neal M.; Biffin, J. Ray; Regtop, Hubert L.


Book ID
121459191
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
162 KB
Volume
16
Category
Article
ISSN
0893-228X

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Several thiosemicarbazone-metal compIexes inhibit the RNA dependent DNA polymerase and the transfonuing ability of Rous sarcoma virus. Some complexes are equally as active as the free l&and whereas the activity of others is greatly enhanced. The 2-forrnyl pyridiue thiosemicarbazone copper (II) compl