Gastrointestinal stromal tumor of the rectal mesentery
β Scribed by Takamori Nakayama; Hayato Hirose; Kiyoshi Isobe; Kou Shiraishi; Takao Nishiumi; Syunji Mori; Yoshiaki Furuta; Masao Kasahara
- Publisher
- Springer Japan
- Year
- 2003
- Tongue
- English
- Weight
- 226 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0944-1174
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## Abstract Somatic, activating mutations of __KIT__ or __PDGFRA__ are early oncogenic events in the majority of sporadic gastrointestinal stromal tumors (GISTs). Also a number of families with GISTs have been described in recent years. The familial GIST syndrome is a rare autosomal dominant disord
## Abstract Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm in the gastrointestinal tract and is associated with mutations of the __KIT__ or __PDGFRA__ gene. In addition, other genetic events are believed to be involved in GIST tumorigenesis. Cytogenetic aberrations as