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π SIMILAR VOLUMES
Glycine-extended gastrin (gastrin-Gly) stimulates proliferation of AR4-2) pancreatic tumor cell line through a specific receptor, different from the gastrin-cholecystokinin B receptor. Our purpose was to determine whether AR4-2) cells produced gastrin-Gly and then whether the peptide was involved in
Bombesin is trophic to normal pancreas and acinar cell adenocarcinoma, but its effects on d u d cell tumors are undetermined. The autocrine growth effects of bombesin on well-differentiated (HPAF, CDI I) and poorly differentiated (CD18, PANC-I) human d u d pancreatic cancer cell lines were investiga
The role of gastrin in the control of growth of renal G40 I cells isolated from a human nephroblastoma (Wilms' tumour) was investigated. G401 cell growth was enhanced in the presence of exogenous gastrin. Addition of anti-gastrin antibodies to serumfree medium significantly inhibited the growth of G