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Gas-liquid chromatographic determination of perazine, thioridazine and thioridazine metabolites in human plasma

✍ Scribed by F.A.J. Vanderheeren; D.J.C.J. Theunis; M.-T. Rosseel

Publisher: Elsevier Science
Year: 1976
Tongue: English
Weight: 378 KB
Volume: 120
Category: Article
ISSN: 1873-3778
DOI: 10.1016/s0021-9673(01)99003-x

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✦ Synopsis

A gas-liquid chromatographic method for the detection of perazine, thioridazine and its major metabolites in human plasma is presented. Repeated extraction, an internal standard and a temperature program with flame ionization detection make possible accurate and reproducible results with patients on therapeutic doses of these drugs. Examples of chromatograms after extraction of plasma are given.

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