Gas-liquid chromatographic methods for the measurement of tolbutamide and chlorpropamide in blood and urine and in pharmaceutical preparations have been developed. In these procedures the drugs were extracted from acidified plasma or urine with chloroform and converted to the corresponding methyl de
Gas chromatographic method of moisture determination
โ Scribed by J. H. Martin; A. M. Knevel
- Publisher
- John Wiley and Sons
- Year
- 1965
- Tongue
- English
- Weight
- 366 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3549
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Thymol in biological samples is analyzed by gas chromatography utilizing a 5% OV-25 column, a flame ionization detector, and eugenol as an internal standard. Samples are extracted with diethyl ether and analyzed without derivatization. The lower limit of detection of thymol in a sample is about 0.01
The gas-liquid chromatography of melphalan and its decomposition products, determined as trimethylsilyl derivatives, is reported. The application of this procedure to the quantification of intact melphalan in a pharmaceutical preparation is described. Keyphrases Melphalan and dosage forms-analysis