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Gas chromatographic-mass spectrometric assay for 2-methoxyethanol and 2-methoxyacetic acid in human plasma and its application to pharmacokinetic studies

✍ Scribed by Tung-Sheng Shih; Ryh-Nan Pan; Jui-Shu Chou; Cheng-Yao Chen; Yoa-Pu Hu

Publisher: Springer
Year: 2001
Tongue: English
Weight: 508 KB
Volume: 54
Category: Article
ISSN: 0009-5893
DOI: 10.1007/bf02492689

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## Abstract A sensitive, selective, specific and rapid liquid chromatographic/electrospray ionization tandem mass spectrometric assay method was developed and validated for the simultaneous quantitation of α‐,β‐arteether (α‐,β‐AE) and its metabolite α‐dihydroartemisinin (DHA) in monkey plasma using