## Abstract The antibiotic streptomycin can be reliably quantitated in injectable pharmaceuticals by GC. The manipulations are not difficult, and total analysis time for duplicate samples is less than twenty minutes. Reaction of the drug with aqueous sodium hydroxide solution generates maltol, whi
Gas chromatographic determination of glycerol guaiacolate in pharmaceutical preparations
β Scribed by Joseph Hudanick
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 211 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
blue T.S. since the indicator change which is somewhat gradual produces a greater variation in results. Similar titrations using azo violet or thymolphthalein were noted to give sharper end points but in each case a green color was observed a t the stoichiometric point. The initial color of these in
CP-Sil-5-CB (20 m, 0.25 mm i.d.) 200 "C -O.S"/min ~ 215 "C ' ) CP-Sil-19-CB (25 m, 0.25 mm i.d.) 225 "C -0.2"/min -229 "C ~ 8"/min ~ 261 "C -4"/min -275 "C. dl CP-Sil-5-CB (10 m, 0.25 mm i.d.) CP-Sil-19-CB (10 m, 0.32 mm i.d.) 190 "C ~ l"/min ~ 250 "C. e, CP-Sil-5-CB (10 m. 0.25 mm i.d.) CP-Sil-19-C
One sample of phenobarbital was eluted quantitatively from the adsorbent with diethyl ether containing 2 z ethanol as a preservative. Prior experimental data showed that diphenylhydantoin was not eluted from the adsorbent with diethyl ether. Preparations containing sodium salts of phenobarbital and/
FFA (free fatty acids), GLC (gas liquid chromatography). G (glycerol), EC (ethylene glycol), GTB (glycerol tribenzoate), EGDB (ethylene glycol dibenzoate).