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Gap Junctions Modulate Survival-Promoting Effects of Fibroblast Growth Factor-2 on Cultured Midbrain Dopaminergic Neurons

โœ Scribed by Doreen SiuYi Leung; Klaus Unsicker; Bernhard Reuss


Book ID
115637768
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
403 KB
Volume
18
Category
Article
ISSN
1044-7431

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Parkinson's disease is characterized by the progressive degeneration of midbrain dopaminergic neurons. Several studies have examined the effects of the dopaminergic neurotrophins growth/differentiation factor 5 (GDF5) and glial cell line-derived neurotrophic factor (GDNF) on these neurons in vitro.