Ganglioside GD2 specificity of monoclonal antibodies to human neuroblastoma cell
โ Scribed by Megumi Saito; Robert K. Yu; N-K.V. Cheung
- Book ID
- 117056740
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 842 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
We published in the journal a new four-color flow cytometric method to help diagnose, stage, monitor, and screen autologous transplant products for children with neuroblastoma (1). The ''four-color'' monoclonal antibody assay involved a ganglioside GD2/fluorescein isothiocyanate (FITC), TAPA CD81/ph
Substantial concentrations of the cell-surface glycosphingolipid, the disialoganglioside GD2, are uniformly present in human neuroblastoma tumors. This ganglioside can also be detected in the plasma of patients with neuroblastoma by direct thin-layer chromatographic analysis. Among 32 neuroblastoma