<p>Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state and from its use in general anaesthesia in human subjects. It has been found to be a naturally-occurring compound in the brain, a metabolite of GABA, the emerging ubi
Gamma-hydroxybutyrate : molecular, functional, and clinical aspects
β Scribed by Tunnicliff, Godfrey; Cash, Christopher D
- Publisher
- Taylor & Francis
- Year
- 2002
- Tongue
- English
- Leaves
- 316
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Table of Contents
Content: Metabolism and Distribution of Gamma-Hydroxybutyrate in the Brain. The Gamma-hydroxybutyrate Receptor in the Brain. Part of the Pharmacological Actions of Gamma-hydroxybutyrate Are Mediated by GABAB Receptors. Membrane Transport of Gamma-hydroxybutyrate. Action of Gamma-hydroxybutyrate on Neuronal Excitability and Underlying Membrane Conductances. Regulation of Central Dopamine by Gamma-hydroxybutyrate. Effects of Gamma-hydroxybutyrate on Sleep. Gamma-hydroxybutyrate and Absence Seizure Activity. Behavioral Pharmacology of Gamma-hydroxybutyrate. Therapeutic Uses of Gamma-hydroxybutyrate. Abuse Potential and Toxicology of Gamma-hydroxybutyrate. 4-Hydroxybutyric Aciduria. Gamma-Hydroxybutyrate and Oxidative Stress. The Role of Gamma-hydroxybutyrate in Brain Function.
β¦ Subjects
GABA. Neurochemistry. GABA -- Therapeutic use. Sodium Oxybate -- metabolism. Brain -- metabolism. Sodium Oxybate -- therapeutic use. MEDICAL -- Pain Medicine. MEDICAL -- Psychiatry -- Psychopharmacology.
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