Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by loss of memory and cognition and by senile plaques and neurofibrillary tangles in brain. Amyloid-beta peptide, particularly the 42-amino-acid peptide (Abeta(1-42)), is a principal component of senile plaques and is
Galantamine protects against oxidative stress induced by amyloid-beta peptide in cortical neurons
✍ Scribed by Joana B. Melo; Carla Sousa; Pedro Garção; Catarina R. Oliveira; Paula Agostinho
- Book ID
- 109027749
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 665 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0953-816X
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Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition of amyloid-beta peptide (Abeta), a peptide that as both oligomers and fibrils is believed to play a central role in the development and progress of AD by inducing oxidative stress in brain. Therefore, treatment
Oxidative stress has been implicated in the pathophysiology of a number of diseases, including neurodegenerative disorders such as Alzheimer's disease (AD), a neurodegenerative disorder associated with cognitive decline and enhanced oxidative stress. Amyloid-beta peptide(1-42) (Abeta(1-42)), one of