๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Galactosyl Prodrug of Ketorolac: Synthesis, Stability, and Pharmacological and Pharmacokinetic Evaluations

โœ Scribed by Curcio, Annalisa; Sasso, Oscar; Melisi, Daniela; Nieddu, Maria; La Rana, Giovanna; Russo, Roberto; Gavini, Elisabetta; Boatto, Gianpiero; Abignente, Enrico; Calignano, Antonio; Rimoli, Maria Grazia


Book ID
118180096
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
262 KB
Volume
52
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Synthesis and evaluation of Ketorolac es
โœ Hea-Jeong Doh; Won-Jea Cho; Chul-Soon Yong; Han-Gon Choi; Jung Sun Kim; Chi-Ho L ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 145 KB

Alkyl esters of ketorolac were synthesized as potential prodrugs for transdermal delivery and evaluated to determine the relationship between their skin permeation characteristics and their physicochemical properties. Solubility of the prodrugs in various vehicles was determined at room temperature

Novel amides and esters prodrugs of olme
โœ Jin-Hun Park; Jeong-Soo Chang; Mohammed I. El-Gamal; Won-Kyoung Choi; Woong San ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 560 KB

Synthesis of novel amides and esters prodrugs of olmesartan is described. Their in vitro stability in rat plasma was tested. The results showed that the ester derivative IIa with n-octyl substituted dioxolone moiety was rapidly converted into olmesartan within 30 min. The pharmacokinetic parameters