𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Galactosamine-induced fulminant hepatic necrosis in unanesthetized canines

✍ Scribed by J A Diaz-Buxo; S Blumenthal; D Hayes; P Gores; B Gordon


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
428 KB
Volume
25
Category
Article
ISSN
0270-9139

No coin nor oath required. For personal study only.

✦ Synopsis


Abbreviations: FHF, fulminant hepatic failure; IV, intravenous; AST, aspartate transtaneous cannulation with polyurethane single lumen catheters (Medaminase; ALT, alanine transaminase; PT, prothrombin time; PTT, partial thromboplastin time.

Comp MCF10, Harleysville, PA), using the Seldinger technique 16 just From the Departments of 1 Medicine, 2 Comparative Medicine, and 3 Surgery, Carolinas before injection of D-galactosamine. The procedure was performed Medical Center, Charlotte, NC.

employing sterile technique under ketamine (2 mg/kg, intravenous


📜 SIMILAR VOLUMES


Selective blockade of mGlu5 metabotropic
✍ Cristiano R. Jesse; Ethel A. Wilhelm; Cristiani F. Bortolatto; Lucielli Savegnag 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 432 KB

## Abstract This study was designed to investigate the influence of 2‐methyl‐6‐phenylethynyl pyridine hydrochloride (MPEP), an antagonist of metabotropic glutamate receptor subtype 5, in lipopolysaccharide (LPS) and d‐galactosamine (d‐GalN)‐induced fulminant hepatic failure in mice. Mice were given

Hepatitis B virus mutations associated w
✍ Thomas F. Baumert; Chun Yang; Peter Schürmann; Josef Köck; Christian Ziegler; Ca 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 451 KB 👁 1 views

Hepatitis B virus (HBV) core promoter mutations have been implicated in the pathogenesis of fulminant hepatitis B. Due to the limited availability of primary human hepatocytes, the functional characterization of HBV mutants has been performed predominantly in transformed cells, which may not represe

Possible involvement of reactive oxygen
✍ Yosuke Osawa; Masahito Nagaki; Yoshiko Banno; Yasuhiro Yamada; Motoaki Imose; Yo 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 353 KB

Intravenous administration of tumor necrosis factor-alpha (TNF-alpha) (0.5 microg/mouse) caused hepatocyte apoptosis in BALB/c mice when they were sensitized with D-galactosamine (GalN, 20 mg/mouse). Activation of nuclear factor kappa B (NF-kappa B) and expression of apoptotic Bcl-2 family members w

Hypothyroidism minimizes liver damage an
✍ Rafael Bruck; Ran Oren; Haim Shirin; Hussein Aeed; Moshe Papa; Zipora Matas; Lil 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 216 KB 👁 1 views

Recent data from animal studies suggest that induced hypothyroidism prevents the hyperdynamic circulation in portal vein ligated rats, liver cirrhosis in rats chronically treated with thioacetamide (TAA), and immune-mediated acute liver injury induced in mice by concanavalin A. Therefore, the aim of