𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Gain of Function of a p53 Hot Spot Mutation in a Mouse Model of Li-Fraumeni Syndrome

✍ Scribed by Gene A. Lang; Tomoo Iwakuma; Young-Ah Suh; Geng Liu; V.Ashutosh Rao; John M. Parant; Yasmine A. Valentin-Vega; Tamara Terzian; Lisa C. Caldwell; Louise C. Strong; Adel K. El-Naggar; Guillermina Lozano


Book ID
116352421
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
582 KB
Volume
119
Category
Article
ISSN
0092-8674

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Evaluation of the molecular mechanisms i
✍ Silvia Capponcelli; Elena Pedrini; Maria Antonietta Cerone; Valeria Corti; Silvi πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 325 KB

The TP53 tumor suppressor gene is the most frequent target for genetic alterations in human cancer. TP53 gene alterations may result in the gain of oncogenic functions such as neoangiogenesis and resistance to therapy. The TP53 germ line mutation c.659A>C (p.Y220S) was identified in stored DNA from