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Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patients

✍ Scribed by M. Łastowska; S. Cotterill; A.D.J. Pearson; P. Roberts; A. McGuckin; I. Lewis; N. Bown

Book ID
117663991
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
782 KB
Volume
33
Category
Article
ISSN
0959-8049

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Deletions of chromosome arm 1p and amplification of the MYCN oncogene are well-recognized genetic changes in neuroblastoma cells. Technical difficulties in cytogenetic analysis of this tumour have hampered the recognition of other recurring abnormalities, but recent use of molecular cytogenetic tech