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GABA-B receptor: Possible target for Parkinson's disease therapy

✍ Scribed by Atsushi Nambu


Book ID
113616899
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
129 KB
Volume
233
Category
Article
ISSN
0014-4886

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## Abstract Hyperactivity in the subthalamic nucleus (STN) projections to the globus pallidus medialis (GPM) has been established as a crucial feature of parkinsonism in animal models of Parkinson's disease (PD). Recent experiments blocking the STN glutamatergic output to GPM or lesioning the STN s