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GABA-A receptor impairment in cerebellar ataxia with anti-glutamic acid decarboxylase antibodies

✍ Scribed by Hosoi, Yasushi; Suzuki-Sakao, Makiko; Terada, Tatsuhiro; Konishi, Takashi; Ouchi, Yasuomi; Miyajima, Hiroaki; Kono, Satoshi


Book ID
121597092
Publisher
Springer
Year
2013
Tongue
English
Weight
766 KB
Volume
260
Category
Article
ISSN
0340-5354

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Glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the conversion of glutamate to β₯-aminobutyric acid (GABA). Anti-GAD antibody (GAD-Ab) is considered to be a marker for stiff person syndrome (SPS), 1 insulin-dependent diabetes mellitus (IDDM), and polyendocrine autoimmune syndrome. 2 Add