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G-quadruplex DNA: a potential target for anti-cancer drug design

✍ Scribed by Haiyong Han; Laurence H Hurley

Book ID
117340322
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
238 KB
Volume
21
Category
Article
ISSN
0165-6147

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## Abstract The concept of a G‐quartet, a unique structural arrangement intrinsic to guanine‐rich DNA, was first introduced by Gellert and colleagues1 over 40 years ago. For decades, it has been uncertain whether the G‐quartet and the structure that it gives rise to, the G‐quadruplex, are purely in