𝔖 Bobbio Scriptorium
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G protein mutations in human disease

✍ Scribed by Lee S. Weinstein; Andrew Shenker


Book ID
107740530
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
720 KB
Volume
26
Category
Article
ISSN
0009-9120

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Heterotrimeric guanine nucleotide binding proteins (G proteins) couple a large number of cell surface receptors to their intracellular effector molecules, such as enzymes or ion channels. Mutations of G proteins can lead to either activation or inactivation of the corresponding signal transduction p