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G-CSF treatment prevents cyclophosphamide acceleration of autoimmune diabetes in the NOD mouse

✍ Scribed by Karine Hadaya; Hassen Kared; Annie Masson; Lucienne Chatenoud; Flora Zavala


Book ID
116613906
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
322 KB
Volume
24
Category
Article
ISSN
0896-8411

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The development of diabetes in non-obese diabetic (NOD) mice, which normally takes between 3 and 7 months, can be accelerated by cyclophosphamide (CY) injections, with rapid progression to diabetes within only 2Β±3 weeks. This insulin-dependent diabetes mellitus (IDDM) can be prevented or delayed in