We describe a previously unreported glucose-6-phosphate dehydrogenase (G6PD) variant. G6PD Huntsville was found in a Caucasian male, resident of Huntsville, Alabama who was investigated for otherwise unexplained chronic hemolytic anemia. An unusual feature of this unique, apparently hemolytic, G6PD
G-6-PD Guadalajara. A new mutant associated with chronic nonspherocytic hemolytic anemia
✍ Scribed by G. Vaca; B. Ibarra; F. Romero; N. Olivares; J. M. Cantú; E. Beutler
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 234 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A new deficient variant of glucose-6-phosphate dehydrogenase (G6PD) causing severe congenital nonspherocytic hemolytic anemia (CNSHA) is described. The variant enzyme, characterized by slow electrophoretic mobility, extreme in vivo and in vitro lability, high Km for G6P and strongly acidic pH optimu
Glucose-6-Phosphate Dehydrogenase (G6PD) is the most common enzymopathy of humans, affecting >400 million people. It is associated with a range of clinical manifestations such as neonatal jaundice, drug or infection-mediated hemolytic crisis, favism, and less commonly, chronic nonspherocytic anemia