## Abstract ## Background. The purpose of this study was to test the Union Internationale Contre le Cancer (UICC)/TNM category–based head and neck cancer stage grouping systems proposed in the literature for their ability to create clinically relevant prognostic groups of like‐patients with cancer
Future of the TNM classification and staging system in head and neck cancer
✍ Scribed by Robert P. Takes; Alessandra Rinaldo; Carl E. Silver; Jay F. Piccirillo; Missak Haigentz Jr; Carlos Suárez; Vincent Van der Poorten; Robert Hermans; Juan Pablo Rodrigo; Kenneth O. Devaney; Alfio Ferlito
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 195 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Staging systems for cancer, including the most universally used TNM classification system, have been based almost exclusively on anatomic information. However, the question arises whether staging systems should be based on this information alone. Other parameters have been identified that should be considered for inclusion in classification systems like the TNM. This is all the more important, as a shift toward nonsurgical treatments for head and neck cancer has been made over the years. For these treatment modalities tumor/biologic characteristics next to anatomic information may be particularly important for treatment choice and outcome. The shortcomings of the current TNM classification system will be discussed, along with suggestions for improvement and expansion of the TNM system based on tumor, patient, and environment‐related factors. Further improvement of the TNM classification is expected to result in better treatment choices, outcome and prognostication of patients with head and neck cancer. © 2010 Wiley Periodicals, Inc. Head Neck, 2010
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## BACKGROUND. The fifth edition of the TNM classification contains a number of changes concerning head and neck tumors. The division of Stage IV tumors into three subcategories marks a significant expansion of the stage grouping procedure. ## METHODS. In a retrospective study, the clinical cou