A solid phase chemistry approach utilizing Mitsunobu chemistry, amine functionalization, and parallel purification was used to produce a diverse library of benzothiophene analogs. These analogs were used to advance the SAR of this class of molecules and give new directions for future studies.
β¦ LIBER β¦
Future challenges facing the development of specific active-site-directed synthetic inhibitors of MMPs
β Scribed by P. Cuniasse; L. Devel; A. Makaritis; F. Beau; D. Georgiadis; M. Matziari; A. Yiotakis; V. Dive
- Book ID
- 116308373
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 474 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0300-9084
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