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Fused polyaza-heterocycles and 1,3,4-thiadiazoles via a tricyano synthon

✍ Scribed by Kamal M. Dawood; Mohamed A. Raslan

Publisher
Journal of Heterocyclic Chemistry
Year
2008
Tongue
English
Weight
330 KB
Volume
45
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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Treatment of 2‐cyano‐3‐phenyl‐2‐pentenedinitrile with some heterocyclic diazonium salts afforded the corresponding heterocyclic hydrazones. Some of the latter hydrazones were converted into fused polyaza‐heterocycles upon boiling in pyridine. Reaction of 2‐cyano‐3‐phenyl‐2‐pentenedinitrile with phenylisothiocyanate gave a tricyano‐thiole derivative which on treatment with hydrazonoyl chlorides and 1‐(benzothiazol‐2‐yl)‐2‐bromoethanone furnished 1,3,4‐thiadiazole and thiazole derivatives, respectively.

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