## _BSTRACT Kidney samples from children with the inborn metabolic disease cystinosis contain 4 times more selenium (Se) than do kidney samples from normal individuals (p = 0.1). However. when cultured skin frbroblasts from cystinotic patients and normal control individuals are incubated in Se-D,L
โฆ LIBER โฆ
Further studies on the effect of chloroquine on the uptake, metabolism and intracellular translocation of [35S]cystine in cystinotic fibroblasts
โ Scribed by C.J. Danpure; P.R. Jennings; D.A. Fyfe
- Book ID
- 119120410
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 732 KB
- Volume
- 885
- Category
- Article
- ISSN
- 0167-4889
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We examined the route of uptake of 2-aminoethylphosphonate (NEthPo) and of phenylphosphonate (PhePo; 10 mM each) in perfused liver by 31 P-NMR. Uptake of NEthPo was concentrative. The rate of uptake was reduced to 21 AE 2% (n = 3; all percentages refer to control rates) by substituting choline for N