Further New Secoatisane Diterpenoids from the Chinese Mangrove Excoecaria agallocha L.

✍ Scribed by Ji-Dong Wang; Zhen-Yu Li; Wen-Sheng Xiang; Yue-Wei Guo

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: German
• Weight: 78 KB
• Volume: 89
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200690136

✦ Synopsis

Four new 3,4-seco-ent-atisane diterpenoids, agallochaols G -J (1 -4), were isolated from the stems and leaves of the Chinese mangrove Excoecaria agallocha L. Their structures were established on the basis of detailed spectroscopic analysis, chemical evidence, and by comparison with the literature data of related compounds.

Introduction. The mangrove Excoecaria agallocha L.(Euphorbiaceae) is a rich source of diterpenoids with different skeletons [1 -5]. We previously reported the isolation and structure elucidation of the new compounds agallochaols A -F from the title plant [6] [7]. During our continuing search for medicinal agents from mangroves, we now report the isolation and structure elucidation of four additional new minor diterpenoids, agallochaols G -J (1 -4).