Further family studies on the genetic control of β2-glycoprotein I concentration in human serum
✍ Scribed by Hartwig Cleve; Christian Rittner
- Publisher
- Springer
- Year
- 1969
- Tongue
- English
- Weight
- 266 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0340-6717
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Five allotypes, Lpm 1, Lpm 2, Lpm 3, Lpm 4, and Lpm 5, were detected by isoimmunization in mink sera. Immunoelectrophoresis, preparative ultracentrifugation, and histochemical tests for lipids and esterase permitted reference of these alloantigenic markers to a very high density alpha2-lipoprotein.
By means of alloimmunization of mink, two new antigens, Lpm-7 and Lpm-8, were detected in their sera. Lpm-7 and Lpm-8 allospecificities were referred to a very high density alpha2-lipoprotein (Lpm) by the following criteria: histochemical tests, immunoelectrophoresis, preparative ultracentrifugation