𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Further evidence of the protonation of the C-terminal of the poly-γ-benzyl-L-glutamate helix by acids

✍ Scribed by Hiroshi Watanabe; Koshiro Yoshioka

Publisher
Wiley (John Wiley & Sons)
Year
1966
Tongue
English
Weight
313 KB
Volume
4
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.

✦ Synopsis

The change of the specific Kerr constant upon the addition of several acids to poly-5benzyl-kglutamate solution in ethylene dichloride has been measured by the rectangular pulse method. The addition of a small amount of strong acid (trifluoroacetic acid, trichloroacetic acid, monochloroacetic acid, or hydrogen chloride) caused a rapid decrease of the specific Kerr constant. On the other hand, the effect of weak acids (formic acid, acetic acid, and propionic acid) was small. These facts show that the apparent dipole moment of a helical poly-7-benzyl-cglutamate molecule is considerably diminished by the protonation of terminal peptide groups. The electric conductivity of poly-ybenzyl-cglutamate solution in ethylene dichloride-dichloroacetic acia mixtures has been measured. It was found that the specific conductivity per unit concentration of poly-y-benzyl-cglutamate increased considerably at small fractions of dichloroacetic acid. This showa that poly-y-benzyl-L-glutamate can react as a base (proton acceptor) with dichloroacetic acid. This result also confirms the previous conclusion.

📜 SIMILAR VOLUMES

Helix–coil transition of poly(γ-benzyl-L
Helix–coil transition of poly(γ-benzyl-L-glutamate) in the dioxane–dichloroacetic acid mixture
✍ A. K. Gupta; C. Dufour; E. Marchal; H. Benoit 📂 Article 📅 1975 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 367 KB 👁 1 views

## Abstract The thermal helix–coil transition of four samples of poly(γ‐benzyl‐L‐glutamate) in the dioxane–dichloroacetic acid (DCA) mixture was studied by optical rotatory dispersion method. The transition occurred at very high DCA content (97.5% by weight) in this system. The transition parameter

Solvent dependence of the helix–coil tra
Solvent dependence of the helix–coil transition of poly-γ-benzyl-L-glutamate. A PMR study
✍ Luciano Ferrara; Piero A. Temussi 📂 Article 📅 1973 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 395 KB 👁 2 views

## Abstract The coil to helix conformational transitions undergone by poly‐γ‐benzyl‐~L~‐glutamate in solutions of haloacetic acids and various cosolvents were studied by means of proton magnetic resonance. The results indicate a very small solvent dependence of the α‐CH Helix–coil chemical shift di

Enthalpy change of the coil–helix transi
Enthalpy change of the coil–helix transition of poly(γ-benzyl L-glutamate) in dichloroacetic acid–1,2-dichloroethane mixtures
✍ Akihiro Kagemoto; Ryoichi Fujishiro 📂 Article 📅 1968 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 254 KB 👁 1 views

By combining the heat of dilution of a poly (y-benzyl L-glutamate)-dichloroacetic acid-1,2-dichloroethane solution with the corresponding heat of mixing of two solvents, the integrated heat of the coil-helix transition of poly(y-benzyl L-glutamate) in the solution was estimated to be about 750 cal/m

On the flexibility of poly(γ-benzyl L-gl
On the flexibility of poly(γ-benzyl L-glutamate) in helicogenic solvents
✍ Yoshio Muroga; Mitsuru Nagasawa 📂 Article 📅 1998 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 110 KB 👁 1 views

The molecular-weight dependence of the rms radius of gyration »R 2 g … 1/2 of poly(gbenzyl L-glutamate ) (PBLG) in helicogenic solvents shows negative and positive deviations from expectations for an intact and rigid a-helix in the higher and lower molecular-weight ranges, respectively. In order to