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Further evidence for distorted coformation of ring b in some 6β-substituted Δ4-3-ketosteroids

✍ Scribed by Kazuo Tori; Yoshihiro Terui; Masaru Moriyama; Kaoru Kuriyama

Publisher
Elsevier Science
Year
1968
Tongue
French
Weight
192 KB
Volume
9
Category
Article
ISSN
0040-4039

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✦ Synopsis

On the basis of a PMR study, we previously reported that the B-ring in seveml A'-3-ketostemids having a +substituent bulkier than or equal in size to chlorine is distorted owing to the 1,3-dioxial intern&on between the IO-methyl group and the q-substituent (1). However, scme reservation about this conclusion has been expressed because the Jh,% and J&a values, which led us to the conclusion, were determined by the first-order approximation (2). In order to obtain further evidence for our con-' elusion, we measured the PMR spectm of +bromotestosterone acetate (I), its 19-1~ derivative (II), @-

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