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Further development of the rat Pig-a mutation assay: Measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes

โœ Scribed by Takafumi Kimoto; Satsuki Chikura; Kumiko Suzuki; Xiao mei Kobayashi; Yasuhiro Itano; Katsuyoshi Horibata; Masamitsu Honma; Vasily N. Dobrovolsky; Robert H. Heflich; Daishiro Miura; Yoshinori Kasahara


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
834 KB
Volume
52
Category
Article
ISSN
0893-6692

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## Abstract We previously reported that rat spleen Tโ€cells and peripheral red blood cells that are deficient in glycosylphosphatidylinositol (GPI) synthesis [presumed mutants for the phosphatidylinositol glycan complementation group A gene (__Pigโ€A__)] could be detected by flow cytometry (FCM) as c