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Further development and validation of empirical scoring functions for structure-based binding affinity prediction

✍ Scribed by Renxiao Wang; Luhua Lai; Shaomeng Wang


Book ID
110347700
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
204 KB
Volume
16
Category
Article
ISSN
0920-654X

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Accurately predicting the binding affinities of large sets of protein-ligand complexes efficiently is a key challenge in computational biomolecular science, with applications in drug discovery, chemical biology, and structural biology. Since a scoring function (SF) is used to score, rank, and identi