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Further Characterization of the Major and Minor RabbitFMO1Promoters and Identification of both Positive and Negative Distal Regulatory Elements

โœ Scribed by Zhaohui Luo; Ronald N. Hines

Book ID
115566683
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
795 KB
Volume
346
Category
Article
ISSN
0003-9861

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ฮณ-Glutamyl transpeptidase is normally not present in adult rat hepatocytes, but its expression is induced by a range of xenobiotics, including carcinogens and chemopreventive agents. Synthesis of the enzyme is mediated by at least six mRNAs transcribed from tandemly arranged promoters on a single ge