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Functions of histone-modifying enzymes in development

✍ Scribed by Wenchu Lin; Sharon YR Dent


Book ID
116505044
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
210 KB
Volume
16
Category
Article
ISSN
0959-437X

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Recent advances have shown the crucial role of histone-modifying enzymes in controlling gene activation and repression. This led to the 'histone code' hypothesis, which proposes that combinations of histone modifications work in concert to affect specific gene expression. Mounting evidence suggests