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Functionalised pyrrolidinones derived from (S)-pyroglutamic acid by cycloaddition reactions

✍ Scribed by Jonathan H. Bailey; David T. Cherry; Katherine M. Crapnell; Mark G. Moloney; Sung Bo Shim; Mark J. Bamford; R.Brian Lamont


Book ID
104207991
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
779 KB
Volume
53
Category
Article
ISSN
0040-4020

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✦ Synopsis


The ot, l~-unsaturated bicyclic lactams 3a,e, prepared from (S)-pyroglutamic acid. are useful substrates for cycloaddition reactions, giving excellent regio-and diastereocontrol; however, lactam 3e has very superior reactivity with several dienes and dipoles under mild reaction conditions.


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ChemInform Abstract: Pyrrolidinones Deri
✍ Philip W. H. Chan; Ian F. Cottrell; Mark G. Moloney πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 34 KB πŸ‘ 1 views

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