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Functional TLR9 modulates bone marrow B cells from rheumatoid arthritis patients

✍ Scribed by Weronika Rudnicka; Tomasz Burakowski; Ewa Warnawin; Magdalena Jastrzebska; Magdalena Bik; Ewa Kontny; Magdalena Chorazy-Massalska; Anna Radzikowska; Marcin Buler; Pawel Maldyk; Wlodzimierz Maslinski


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
343 KB
Volume
39
Category
Article
ISSN
0014-2980

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✍ M. Broek; L. Boeije; T. Swaak; R. Smeenk; L. Aarden πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 726 KB

Rheumatoid arthritis is a T cell-mediated autoimmune disease. The lack of knowledge of the involved target antigens severely hampers research on relevant T cells in patients. Here we describe the functional analysis of freshly isolated T cells from the peripheral blood and the site of the lesion (sy