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Selective induction of igm rheumatoid factors by cd14+ monocyte-lineage cells generated from bone marrow of patients with rheumatoid arthritis

✍ Scribed by Shunsei Hirohata; Tamiko Yanagida; Michinobu Koda; Masahito Koiwa; Shin'Ichi Yoshino; Tkahiro Ochi

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 544 KB
Volume: 38
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780380315

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## Abstract ## Objective To determine the signal transduction pathways in CD14+ synovial cells from patients with rheumatoid arthritis (RA) after CD40 ligation, and to examine their role in amplifying synovial inflammation in affected joints. ## Methods Expression of messenger RNA was analyzed u