## Abstract The effect of T cell‐replacing factor (TRF) on B cells was studied in spleen cell cultures from athymic nu/nu mice with particular emphasis on its possible role in proliferation and/or differentiation of precursor cells. In contrast to B cell mitogens, such as lipopolysaccharide, TRF d
Functional Thy-1+ cells in cultures of spleen cells from nu/nu mice
✍ Scribed by Gunther Dennert; Robert Hyman
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 734 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Mice carrying the nude mutation (nu/nu) lack a functioning thymus and do not contain detectable levels of immunocompetent T cells. We now report that nu/nu mice do have lymphocytes which can be activated __in vivo__ by heterologous erythrocytes and a Lyt‐1 T cell‐derived factor (interle
## Abstract Thymic tissue of C57BL/6 mice and DA rats was cultured. After 6–8 weeks, cultures were analyzed for their capacity to absorb anti‐Thy‐1 serum, and for the expression of Thy‐1 on the surface of different cell types by means of the indirect peroxidase labeling method. Three main cell type