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Functional study of T lymphocyte responsiveness in patients with dementia of the Alzheimer type

โœ Scribed by A. Leonardi; L. Arata; G. Bino; M. Caira; M. Farinelli; C. Parodi; M. Scudeletti; G.W. Canonica

Book ID
119107341
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
306 KB
Volume
22
Category
Article
ISSN
0165-5728

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Alaproclate: A pharmacokinetic and bioch
Alaproclate: A pharmacokinetic and biochemical study in patients with dementia of Alzheimer type
โœ I. Bergman; G. Brane; C. G. Gottfries; K. -G. Jostell; I. Karlsson; L. Svennerho ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer ๐ŸŒ English โš– 450 KB

Alaproclate, a specific inhibitor of neuronal serotonin re-uptake, was given to 12 patients with dementia of Alzheimer type. The drug was rapidly absorbed and an elimination half-life of 7.1 +/- 0.9 h (+/- SD, n = 8) was calculated. Plasma protein binding for alaproclate was 82 +/- 1%. Two weeks of