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Functional significance of MMP-2 and MMP-9 expression by human malignant oral keratinocyte cell lines

✍ Scribed by C.M Robinson; A.M Stone; J.D Shields; S Huntley; I.C Paterson; S.S Prime

Book ID: 113988479
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 268 KB
Volume: 48
Category: Article
ISSN: 0003-9969
DOI: 10.1016/s0003-9969(03)00172-9

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## Abstract P450 aromatase catalyzes the conversion of androgens to estrogens and plays a key role in the cell growth of hormone‐dependent breast cancer in postmenopausal women. On the other hand, matrix metalloproteinases (MMPs), which can degrade almost all components of the extracellular matrix,